He continued to study medicine with Thomas Sydenham as his mentor. (Wikipedia) He had an unsuccessful attempt to prevent James II from reaching the throne, and, as a result of his failure, he had been obliged to flee England. He did not return to England until 1689, when James II had been removed from power. It only took one year until he published his most important work: An Essay Concerning Humane Understanding. He had been inspired from the works of Decartes when he wrote the essay. Locke also paid great interest to politics, which motivated him in writing the Two Treatises of Government. His work related to the fact that the state has to protect the rights that its citizens have, including the right to property.

The fact that he considered the people to be more important than the state and that freedom of religion was vital in order for society to thrive had made him a few enemies....

Even the government felt that his works encouraged people to rebel against the state. He continued to publish a series of essays over the years with the intention of raising people's morals by demonstrating that they had been entitled to much more than what they received from the government. (The European Graduate School)
Locke had no rival when concerning philosophers from the Enlightenment era, with the influence that his works have had on philosophy and politics being remarkable. His essay, Two Treatises of Government, had managed to inspire numerous people in making a stand for their rights.

Works cited:

1. (2008). "John Locke." Retrieved May 23, 2009, from The European Graduate School Web site: http://www.egs.edu/resources/locke.html

2. (2009). "John Locke." Retrieved May 23, 2009, from Wikipedia Web site: http://en.wikipedia.org/wiki/John_Locke